Supplements 7 topics · 58 claims

The most-studied sports supplement — and one of the most-hyped. The evidence is rock-solid for muscle, strength, safety and dosing (no loading needed, mon…

One of the most-purchased supplements, with a mixed record. Refuted for preventing colds in the general population (regular use trims cold duration only m…

An essential mineral and top-selling supplement. Well-supported for improving glycemic control (mainly in deficiency or diabetes) and as an osmotic laxati…

A mitochondrial antioxidant sold widely for heart and muscle health. Best-supported for improving sperm parameters (a surrogate fertility endpoint) and a…

Ketone salts/esters that raise blood BHB without carb restriction. They reliably raise ketones and blunt post-meal glucose, with real cardiac-output and a…

NMN/NR longevity supplements. They reliably raise blood NAD+, but translating that into improved physical function or healthspan in humans is contested —…

A red-wine polyphenol marketed for longevity. It does NOT directly activate SIRT1 as originally claimed, and lifespan extension is contested — the foundat…