Medications 8 topics · 54 claims

Cholesterol-lowering drugs. Strong evidence they lower LDL and cut cardiovascular events (clearest in secondary prevention; smaller but real in primary pr…

GLP-1 and GLP-1/GIP receptor agonists — semaglutide (Ozempic/Wegovy), tirzepatide (Mounjaro/Zepbound), liraglutide. Strong evidence they cause major weigh…

First-line type-2-diabetes drug, also used off-label for longevity. Strong evidence it prevents/delays diabetes, lowers insulin resistance, and causes mod…

Testosterone therapy (TRT) for men with low testosterone (hypogonadism). The evidence splits cleanly by outcome: it reliably builds muscle and improves se…

An oral cholesterol-absorption blocker, often added to a statin. Strong evidence it lowers LDL (~18%) and, added to a statin, further cuts cardiovascular…

Injectable cholesterol drugs (evolocumab, alirocumab). Strong evidence they cut LDL ~50–60% and reduce cardiovascular events, and they modestly lower lipo…

An oral non-statin LDL-lowering drug, useful for statin-intolerant patients. Strong evidence it lowers LDL (~20%) and reduces cardiovascular events (CLEAR…

Testosterone-derived muscle-building drugs. They roughly double training-driven muscle gain, but independent evidence ties them to real harms — raised car…