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Supplements · Metabolic & Cardiometabolic

magnesium decreases blood pressure

In plain terms: Can taking magnesium lower your blood pressure?

Leans support Supplements 🔬 Includes disconfirming

Part of: 🧪 magnesium

RefutedContestedStrong support
consensus score 0.52

Modestly—roughly 2–3 mmHg in most people (more in those with hypertension, diabetes or low magnesium), so real but small.

Evidence ladder

How far up the ladder this claim has climbed. A high consensus on a low rung means "consistent so far," not "proven in people."

Top evidence so far: All trials, pooled (Meta-analysis)

MechanismIn-vitroAnimalObservationalRCTMeta-analysis

How the studies fall

5 support 1 contradict 0 tested null 3 mixed · 9 sources, 6 independent groups

What the evidence shows

Magnesium supplementation produces a **modest** blood-pressure reduction (~2–3 mmHg systolic in normotensives; larger, ~5–6 mmHg, in type-2 diabetics/hypertensives), most reliable at >300 mg/day for >12 weeks. Newer umbrella/pooled reviews note the effect is inconsistent across populations, tempering an otherwise consistent direction. measured_by:: [[blood pressure]]

The evidence (9)

SourceGradeStanceQualityFinding
Eriksson & Kohvakka
1995 · Ann Nutr Metab
RCT mixed low Mg lowered SBP/DBP in insulin-dependent but not non-insulin-dependent diabetics — population-dependent.
Zhang et al.
2016 · Hypertension
meta-analysis supports moderate MA 34 double-blind RCTs (n=2028): Mg ~368 mg/d ~3 mo reduced SBP 2.00 / DBP 1.78 mmHg; dose-response, causal inference.
Sacks et al.
1998 · Hypertension
RCT contradicts moderate Normotensive women with low mineral intake (RCT): Mg supplements did NOT lower BP (only potassium did).
Jee et al.
2002 · Am J Hypertens
meta-analysis supports low MA of RCTs: modest, dose-dependent BP reduction; results heterogeneous across trials.
Behers et al.
2024 · Nutrients
meta-analysis supports moderate SR/subgroup MA, general normotensive population: Mg reduced SBP by -2.79 mmHg; dose/duration-optimized analysis.
Zhao et al.
2020 · Diabetes Metab Res Rev
meta-analysis supports moderate Same SR/TSA: Mg supplementation also reduced SBP and DBP.
Argeros et al.
2025 · Hypertension
meta-analysis mixed moderate 2025 SR/MA (Hypertension): reports of Mg effect on BP inconsistent across hypertensive vs normotensive populations.
Asbaghi et al.
2021 · Biol Trace Elem Res
meta-analysis supports moderate MA in T2D: SBP -5.78 mmHg, DBP -2.50 mmHg; significant for >300 mg/day, >12 wk, inorganic forms; no weight/BMI change.
Alharran et al.
2024 · Curr Ther Res Clin Exp
meta-analysis mixed moderate Umbrella MA of RCTs: prior meta-analyses gave conflicting BP results; effect present but heterogeneous.

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