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Diets

cruciferous vegetables decreases cancer risk

In plain terms: Does eating cruciferous vegetables lower cancer risk?

Strong support Diets
RefutedContestedStrong support
consensus score 0.67

Yes as an observational association (~10-20% lower risk for several cancers), but it is correlational, not proof that the vegetables themselves cause the reduction.

Evidence ladder

How far up the ladder this claim has climbed. A high consensus on a low rung means "consistent so far," not "proven in people."

Top evidence so far: All trials, pooled (Meta-analysis)

MechanismIn-vitroAnimalObservationalRCTMeta-analysis

How the studies fall

7 support 0 contradict 0 tested null 3 mixed · 10 sources, 7 independent groups

The evidence (10)

SourceGradeStanceQualityFinding
Yu
2022 · Front Nutr
meta-analysis mixed moderate Meta-analysis of cohort studies found only weak/inconsistent association between cruciferous intake and bladder cancer risk.
Li
2024 · Gynecol Obstet Invest
meta-analysis supports moderate Dose-response meta-analysis found cruciferous vegetable consumption associated with lower ovarian cancer risk.
Ren
2024 · Crit Rev Food Sci Nutr
meta-analysis supports moderate Meta-analysis of 89 studies found highest cruciferous intake associated with ~19% lower gastrointestinal cancer risk with a dose-response.
Tabatabaei
2025 · J Cancer Prevention
observational supports moderate In pooled prospective cohorts, cruciferous vegetable intake was associated with ~18% lower lung cancer risk (RR 0.82), though without a clear non-linear dose-response.
Guo
2024 · J Food Sci
meta-analysis supports moderate Umbrella review of 22 meta-analyses found cruciferous vegetable intake associated with reduced risk across multiple cancers.
Long
2023 · Urologia Internationalis
meta-analysis mixed low The association between cruciferous vegetable intake and prostate cancer risk was weak and inconsistent, remaining contentious.
Zheng
2025 · Nutrition Reviews
meta-analysis mixed moderate A dose-response meta-analysis found cruciferous vegetable intake inversely associated with several cancers but with differential, non-uniform effects across cancer types.
Lai
2025 · BMC Gastroenterology
observational supports moderate A dose-response meta-analysis found higher cruciferous vegetable intake associated with reduced colon cancer risk, attributed to glucosinolate-derived isothiocyanates.
Zhang
2024 · Eur J Nutr
meta-analysis supports moderate Updated meta-analysis found cruciferous vegetable intake associated with reduced pancreatic cancer risk.
Baladia
2024 · Nutrients
observational supports moderate A meta-analysis of observational studies found broccoli consumption inversely associated with cancer risk, though results were not fully consistent across studies.

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